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To systematically review epidemiologic and laboratory studies on the etiology of high myopia and its links to pathologic myopia. Causes and risk factors. Pathological Myopia 01 03 2014 This condition is called a staphyloma. . Pathologic myopia or degenerative myopia is defined by certain degenerative changes in the back of the eye. Myopia occurs when the eyeball is. This leads to a bulging of the posterior portion of the eyeball. What is myopia and pathological myopia Myopia also known as being short sighted causes your vision to be blurry in the distance but clearer when looking at things up close. As the eyeball stretches the layers of tissue beneath the retina can develop cracks and atrophy. Pathological myopia causes the eye to elongate which in turn stretches and thins the retina and the sclera of the eye. Pathological myopia can also cause vision loss that glasses or contact lenses cannot correct. Th...