pathological myopia causes
To systematically review epidemiologic and laboratory studies on the etiology of high myopia and its links to pathologic myopia. Causes and risk factors.
Pathological Myopia 01 03 2014
This condition is called a staphyloma.
. Pathologic myopia or degenerative myopia is defined by certain degenerative changes in the back of the eye. Myopia occurs when the eyeball is. This leads to a bulging of the posterior portion of the eyeball.
What is myopia and pathological myopia Myopia also known as being short sighted causes your vision to be blurry in the distance but clearer when looking at things up close. As the eyeball stretches the layers of tissue beneath the retina can develop cracks and atrophy. Pathological myopia causes the eye to elongate which in turn stretches and thins the retina and the sclera of the eye.
Pathological myopia can also cause vision loss that glasses or contact lenses cannot correct. The invasion of new blood vessels from the choroid under the retina is called neovascularisation. The main reason for best-corrected visual acuity loss is complications specific to PM such as myopic maculopathy myopic traction maculopathy and myopic optic neuropathy or glaucoma.
This is due to the eyeball being too long having a lens which is not able to focus light onto the retina properly or having a cornea which is too curved. Pathologic myopia is defined by a presence of typical complications in the fundus posterior staphyloma or myopic maculopathy equal to or more serious than diffuse choroidal atrophy and often occurs in eyes with high myopia. It is important not to confuse pathologic myopia with high myopia.
The definition of pathologic myopia as suggested by the META-PM Study Group describes the morphological abnormalities in the macular region of highly myopic eyes while coexisting changes in the optic nerve head have been mostly omitted. Central vision loss may occur. Myopic macular degeneration MMD is a serious eye condition that can cause vision loss.
This page contains a summary of our information on myopia and pathological myopia. Pathologic myopia is a leading cause of blindness with vision loss occurring from progressive atrophy or CNV formation Limited case series report that intravitreal bevacizumab Avastin may be effective in maintaining or improving visual acuity. Pathologic myopia affects 1-3 of the general population 1 and has been one of the major causes of low vision and blindness worldwide.
Pathologic myopia is a major cause of low vision and blindness worldwide. Regular Medline searches have been performed for the past 20 years using myopia as the basic search term. By the age of sixty 50 of patients with staphylomas in both eyes will be legally blind.
Studies have shown that both genetic and environmental factors both cause and affect the development of pathological myopia 78910Recent studies investigating the genomics of this condition have successfully identified novel loci which may be responsible for the development of this pathological process. As a result these cracks allow unhealthy blood vessels to grow where they may hemorrhage and scar the retina in a way that is similar to what happens in wet macular degeneration. Pathological myopia can cause a reduction in your sight that cannot be corrected with glasses or contact lenses.
In high myopic eyes pathologic myopia also known as myopic macular degeneration myopic maculopathy or degenerative myopia can occur which can lead to visual acuity VA decline. There have been recent advances in the classification system for myopic maculopathy that enables clinicians to describe different types of lesion. Pathological myopia is the second most common cause of choroidal neovascularization CNV after age-related macular degeneration AMD.
Blurred vision results as do a number of possible complications. It is caused by progressive abnormal elongation of the eyeball. Its social and economic burden has been demonstrated by epidemiological studies.
Around 30 of these patients also develop myopic CNVM in the fellow eye as well. Its a very common focusing problem and for most people it can easily be corrected using glasses or contact lenses making vision clear and crisp. PATHOLOGICAL MYOPIA MCNV Myopic choroidal neovascularisation mCNV which is also called pathological myopia is a possible consequence of short-sightedness which causes damage to the retina through an uncontrolled formation of new blood vessels.
High Myopia Causes High myopia is sometimes an inherited genetic condition and is marked by the eyeball stretching and growing too long. 3 Optic nerve damage however relatively often coexists with maculopathy in eyes with pathologic myopia and not. With pathological myopia light rays from nearby objects are not focused properly onto the retina but instead theyre focused on a point in front of the retina.
Pathologic myopia often begins in childhood and is a leading cause of visual impairment worldwide. Pathological myopia means that you are very short sighted and that this has caused degenerative changes to the back of your eye. Pathologic myopia is a major cause of visual impairment worldwide and associated visual loss is due to various lesions of myopic macular degeneration which develop secondary to posterior staphyloma formation and progressive thinning of the RPE choroid with age in addition to an increase in axial length.
However its complications especially posterior staphyloma can also occur in eyes without high myopia myopic. The abstracts of all articles have been scrutinized for relevance and where necessary translations of articles in. This throws off the eyeballs normal proportions so that incoming light focuses in front of the retina instead of on it.
It is important to differentiate between the two diseases as their management and outcomes differ. Pathologic myopia PM is the only myopia that causes the loss of best-corrected visual acuity. Pathologic myopia PM is the only myopia that causes the loss of best-corrected visual acuity.
Known also as pathological myopia and degenerative myopia it most commonly develops in people who are. The main reason for best-corrected visual acuity loss is complications specific to PM such as myopic maculopathy myopic traction maculopathy and myopic optic neuropathy or glaucoma.
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